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CA-125 was initially detected using the murine monoclonal antibody designated OC125. Robert Bast , Robert Knapp and their research team first isolated this monoclonal antibody in 1981. [ 28 ] The protein was named "cancer antigen 125" because OC125 was the 125th antibody produced against the ovarian cancer cell line that was being studied.
CA 15-3, for Carcinoma Antigen 15-3, is a tumor marker for many types of cancer, most notably breast cancer. [1] [2] [3]It is derived from MUC1. [4] CA 15-3 and associated CA 27-29 are different epitopes on the same protein antigen product of the breast cancer-associated MUC1 gene.
Faecal calprotectin (or fecal calprotectin) is a biochemical measurement of the protein calprotectin in the stool.Elevated faecal calprotectin indicates the migration of neutrophils to the intestinal mucosa, which occurs during intestinal inflammation, including inflammation caused by inflammatory bowel disease.
The name of California and its ruler Queen Calafia originate in Las Sergas de Esplandián, a 1510 Spanish chivalric epic written by Garci Rodríguez de Montalvo.. The name of California has its origin in the Spanish epic Las sergas de Esplandián ("The Adventures of Esplandián"), written by Garci Rodríguez de Montalvo in the late 15th and early 16th centuries. [17]
At the start of a syllable, there is a contrast between three nasal consonants: /m/, /n/, and /ɲ/ (as in cama 'bed', cana 'grey hair', caña 'sugar cane'), but at the end of a syllable, this contrast is generally neutralized, as nasals assimilate to the place of articulation of the following consonant [9] —even across a word boundary. [33]
Propositions can be placed on the ballot either through the exercise of the initiative power by the voters or by a vote of the state legislature. The state initiative power was added to the California constitution in 1911 as part of the ethics reform instituted by Governor Hiram Johnson in the early 1910s.
At some point in the early 20th century, the official recordkeepers (census takers, city records, etc.) began grouping together all Californios, Mexicanos, and Native (Indio) peoples with Spanish surnames under the terms "Spanish", "Mexican", and sometimes, "colored"; some Californios even intermarried with Mexican Americans (those whose ...
The Spanish question (Spanish: Cuestión Española) was the set of geopolitical and diplomatic circumstances that marked the relationship between Spain and the United Nations between 1945 and 1955, centred on the UN's refusal to admit Spain to the organization due to Francoist Spain's sympathy for the Axis powers, defeated in World War II.