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Based on positive clinical results of regeneration in periodontology research in the 1980s, research began to focus on the potential for re-building alveolar bone defects using guided bone regeneration. The theory of Guided tissue regeneration has been challenged in dentistry. The GBR principle was first examined by Dahlin et al. in 1988 on rats.
A successful tissue regeneration relies on an appropriate source of stem progenitor cells, growth factors and scaffolds to control the development of the specific tissue. [19] The first component for tissue engineering is an appropriate source of progenitor/stem cells by using cells which are able to differentiate into the desired tissue component.
A free gingival graft is a type of gingival grafting performed to correct acquired deficiencies of the gum tissue around teeth or dental implants.Besides autologous tissues, xenogeneic collagen matrices are using for gingival augmentation after dental implantation. [1]
PETTI Gustavo From Cagliari, Italy has been the first one to have had: "A new attachment: guided tissue regeneration using an amniotic membrane and fibrin glue" Publication: Petti G. (1989) “La rigenerazione parodontale guidata con membrana amniotica e colla di fibrina. (Guided periodontal regeneration with an amniotic membrane and fibrin glue).
Periodontal surgery is a form of dental surgery that prevents or corrects anatomical, traumatic, developmental, or plaque-induced defects in the bone, gingiva, or alveolar mucosa. [1]
The use of lasers in treating periodontal disease has been seen by some dental professionals as controversial. [6] The American Academy of Periodontology stated in 1999 that it was "not aware of any randomized blinded controlled longitudinal clinical trials, cohort or longitudinal studies, or case-controlled studies indicating that 'laser excisional new attachment procedure (or Laser ENAP)' or ...
A possible method for tissue regeneration in adults is to place adult stem cell "seeds" inside a tissue bed "soil" in a wound bed and allow the stem cells to stimulate differentiation in the tissue bed cells. This method elicits a regenerative response more similar to fetal wound-healing than adult scar tissue formation. [69]
The incremental cost-effectiveness ratio (ICER) is a statistic used in cost-effectiveness analysis to summarise the cost-effectiveness of a health care intervention. It is defined by the difference in cost between two possible interventions, divided by the difference in their effect.