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Chromosome 12 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 12 spans about 133 million base pairs (the building material of DNA) and represents between 4 and 4.5 percent of the total DNA in cells. Chromosome 12 contains the Homeobox C gene cluster.
Chromosome 13 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. People normally have two copies of this chromosome. Chromosome 13 spans about 113 million base pairs (the building material of DNA ) and represents between 3.5 and 4% of the total DNA in cells .
Chromosome 1 spans about 249 million nucleotide base pairs, which are the basic units of information for DNA. [4] It represents about 8% of the total DNA in human cells. [5] It was the last completed chromosome, sequenced two decades after the beginning of the Human Genome Project.
In human genetics, Haplogroup J-M172 or J2 [Phylogenetics 1] is a Y-chromosome haplogroup which is a subclade (branch) of haplogroup J-M304. [Phylogenetics 2] Haplogroup J-M172 is common in modern populations in Western Asia, Central Asia, South Asia, Southern Europe, Northwestern Iran and North Africa.
An allele [1] is a variant of the sequence of nucleotides at a particular location, or locus, on a DNA molecule. [2]Alleles can differ at a single position through single nucleotide polymorphisms (SNP), [3] but they can also have insertions and deletions of up to several thousand base pairs.
New genes can be generated from an ancestral gene when a duplicate copy mutates and acquires a new function. This process is easier once a gene has been duplicated because it increases the redundancy of the system; one gene in the pair can acquire a new function while the other copy continues to perform its original function.
The table below shows the human Y-chromosome DNA haplogroups, based on relevant studies, for various ethnic [dubious – discuss] and other notable groups from Europe.The samples are taken from individuals identified with the ethnic and linguistic designations shown in the first two columns; the third column gives the sample size studied; and the other columns give the percentage for each ...
Mitochondrial DNA is replicated by the DNA polymerase gamma complex which is composed of a 140 kDa catalytic DNA polymerase encoded by the POLG gene and two 55 kDa accessory subunits encoded by the POLG2 gene. [31] The replisome machinery is formed by DNA polymerase, TWINKLE and mitochondrial SSB proteins.