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Methylene blue consistently increases blood pressure in people with vasoplegic syndrome ... At high doses, however, methylene blue actually induces methemoglobinemia ...
Low blood pressure is treated with vasopressors such as adrenaline. [6] [13] There is tentative clinical evidence and good theoretical evidence of the benefit of lipid emulsion in severe overdoses of CCBs. [14] Methylene blue may also be used for those with low blood pressure that does not respond to other treatments. [10]
Methylene blue is given as a 1% solution (10 mg/ml) 1 to 2 mg/kg administered intravenously slowly over five minutes. Although the response is usually rapid, the dose may be repeated in one hour if the level of methemoglobin is still high one hour after the initial infusion. Methylene blue inhibits monoamine oxidase, and serotonin toxicity can ...
High fever. Confusion. Seizures. High blood pressure. ... Blood thinners and anticoagulants, like warfarin, due to risk of abnormal bleeding ... Water pills. Methylene blue.
The most widely employed photosensitizer in clinical practice is the phenothiazine derivative, methylene blue, which carries a +1 charge. [27] Methylene blue is also favored due to its long record of safe use in patients, both in surgical staining and the systemic treatment of methemoglobinemia. [28]
Wright's stain is a hematologic stain that facilitates the differentiation of blood cell types. It is classically a mixture of eosin (red) and methylene blue dyes. It is used primarily to stain peripheral blood smears, urine samples, and bone marrow aspirates, which are examined under a light microscope.