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Because some adverse effects may only emerge during chronic use of methylphenidate, a constant watch for adverse effects is recommended. [97] A 2018 Cochrane review found that methylphenidate might be associated with serious side effects such as heart problems, psychosis, and death. The certainty of the evidence was stated as very low.
The long-term effects on mental health disorders in later life of chronic use of methylphenidate is unknown. [204] A 2009 FDA review of 49 clinical trials found that approximately 1.5% of children in clinical trials of medications for ADHD had experienced signs or symptoms of psychosis or mania.
Management of ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome) focuses on symptoms management, as no treatments that address the root cause of the illness are available. [ 1 ] : 29 Pacing, or regulating one's activities to avoid triggering worse symptoms, is the most common management strategy for post-exertional malaise .
People suffered from "chronic or recurrent fatigue", among a large number of other symptoms. [1]: 28–29 The initial link between elevated antibodies and the Epstein–Barr virus led to the name "chronic Epstein–Barr virus syndrome". The CDC renamed it chronic fatigue syndrome (CFS), as a viral cause could not be confirmed in studies.
Side effects vary depending on the type of medication used. Some common side effects of bipolar medications include weight gain and fatigue or drowsiness. These side effects can usually be managed ...
Common side effects include abdominal pain, loss of appetite, and fever. [3] Serious side effects may include psychosis, sudden cardiac death, mania, anaphylaxis, seizures, and dangerously prolonged erection. [3] Safety during pregnancy and breastfeeding is unclear. [5] Dexmethylphenidate is a central nervous system (CNS) stimulant.
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