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3′-Phosphoadenosine-5′-phosphosulfate (PAPS) is a derivative of adenosine monophosphate (AMP) that is phosphorylated at the 3′ position and has a sulfate group attached to the 5′ phosphate. It is the most common coenzyme in sulfotransferase reactions and hence part of sulfation pathways . [ 1 ]
The Public Access to Public Science (PAPs) public access to research funded by specific Federal agencies under the jurisdiction of the House Science committee, including National Aeronautics and Space Administration (NASA), the National Science Foundation (NSF), the National Institute of Standards and Technology (NIST) and the National Weather Service (NWS).
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 is an enzyme that in humans is encoded by the PAPSS1 gene. [5] [6] [7]Three-prime-phosphoadenosine 5-prime-phosphosulfate is the sulfate donor cosubstrate for all sulfotransferase (SULT) enzymes (Xu et al., 2000).
Other names in common use include PAPS-desulfoglucosinolate sulfotransferase, 3'-phosphoadenosine-5'-phosphosulfate:desulfoglucosinolate, and sulfotransferase.
PAPs are highly conserved within eukaryotic species, with >80% amino acid homology in mammalian PAPs, [6] and >70% sequence homology in PAPs of plant origin. [7] However sequence analysis reveals that there is minimal homology between plant and mammal PAPs (<20%), except for the metal-ligating amino acid residues which are identical. [8]
Here is a simplified overview of how PAPSS works [9]. A company issues a payment instrument to their local bank or payment service provider; The payment instruction is sent to PAPSS through the country's central bank and routes it to the beneficiary bank account
Phosphatidate phosphatase regulates lipid metabolism in several ways. In short, it is a key player in controlling the overall flux of triacylglycerols to phospholipids and vice versa, also exerting control through the generation and degradation of lipid-signaling molecules related to phosphatidate. [4]
Papanicolaou stain showing a low-grade squamous intraepithelial lesion (LSIL) from a Pap test. Cell nuclei stained blue.. Papanicolaou stain (also Papanicolaou's stain and Pap stain) is a multichromatic (multicolored) cytological staining technique developed by George Papanicolaou in 1942.