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Syphilis (/ ˈ s ɪ f ə l ɪ s /) is a sexually transmitted infection caused by the bacterium Treponema pallidum subspecies pallidum. [1] The signs and symptoms depend on the stage it presents: primary, secondary, latent or tertiary.
Doxycycline is a broad-spectrum antibiotic that is employed in the treatment of numerous bacterial infections. It is effective against bacteria such as Moraxella catarrhalis, Brucella melitensis, Chlamydia pneumoniae, and Mycoplasma pneumoniae. Additionally, doxycycline is used in the prevention and treatment of serious conditions like anthrax ...
Doxycycline is also used as a prophylactic treatment for infection by Bacillus anthracis and is effective against Yersinia pestis, the infectious agent of bubonic plague. It is also used for malaria treatment and prophylaxis, as well as treating elephantitis filariasis. [10]
No vaccine for syphilis is available as of 2024, but doxycycline postexposure prophylaxis can be used to prevent infections. [68] [69] [70] The outer membrane of T. pallidum has too few surface proteins for an antibody to be effective.
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Bicillin L-A, the only recommended treatment for pregnant women with syphilis, is on backorder because of a manufacturing delay. Drug to treat syphilis on backorder as infection rates grow Skip to ...