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Cyproterone acetate (CPA), sold alone under the brand name Androcur or with ethinylestradiol under the brand names Diane or Diane-35 among others, is an antiandrogen and progestin medication used in the treatment of androgen-dependent conditions such as acne, excessive body hair growth, early puberty, and prostate cancer, as a component of feminizing hormone therapy for transgender individuals ...
The side effects of cyproterone acetate (CPA), a steroidal antiandrogen and progestin, including its frequent and rare side effects, have been studied and characterized.It is generally well-tolerated and has a mild side-effect profile, regardless of dosage, when it used as a progestin or antiandrogen in combination with an estrogen such as ethinylestradiol or estradiol valerate in women.
[4] [19] Both EE and CPA have antigonadotropic effects and act as contraceptives in women by suppressing ovulation. [17] The antigonadotropic effects of EE and CPA also contribute to the antiandrogenic efficacy of the medication by suppressing androgen production by the ovaries. [18]
Other symptoms of PCOS can include: Irregular menstrual cycles. Heavy or long periods. Excess hair growth (hirsutism) Skin changes and acne. Higher body mass index , obesity and difficulty losing ...
Progestin treatment with desogestrel and norgestimate appears to have fewer androgenic side effects and may be safer to use in persons with abnormal lipid levels or hirsutism. [4] Other proposed treatments include antiandrogenic medications, [ 15 ] spironolactone [ 11 ] (in combination with oral contraceptives to prevent menstrual cycle ...
"To meet criteria for PCOS, women will have some of the following symptoms: irregular periods/lack of ovulation, acne, excess hair growth on the face and cysts on ovaries."
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5α-Reductase inhibitors like finasteride, dutasteride, and alfatradiol and the topical nonsteroidal AR antagonist topilutamide (fluridil) are approved for the treatment of pattern hair loss, also known as scalp hair loss or baldness. [40] This condition is generally caused by androgens, so antiandrogens can slow or halt its progression. [41]