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In medicine, nodules are small firm lumps, usually greater than 1 cm in diameter. [ 1 ] [ 2 ] If filled with fluid they are referred to as cysts . [ 2 ] Smaller (less than 0.5 cm) raised soft tissue bumps may be termed papules .
Solitary thyroid nodules are more common in females yet more worrisome in males. Other associations with neoplastic nodules are family history of thyroid cancer and prior radiation to the head and neck. Solitary thyroid nodules are mostly benign colloid nodules. The second most common type is follicular adenoma. [25]
Vocal cord nodules are bilaterally symmetrical benign white masses that form at the midpoint of the vocal folds. [1] Although diagnosis involves a physical examination of the head and neck , as well as perceptual voice measures, visualization of the vocal nodules via laryngeal endoscopy remains the primary diagnostic method.
Lung nodules can also occur in immune disorders, such as rheumatoid arthritis or granulomatosis with polyangiitis, or organizing pneumonia. A solitary lung nodule can be found to be an arteriovenous malformation, a hematoma or an infarction zone. It may also be caused by bronchial atresia, sequestration, an inhaled foreign body or pleural plaque.
These nodules occur almost exclusively in association with rheumatoid arthritis. Very rarely do rheumatoid nodules occur as rheumatoid nodulosis (multiple nodules on the hands or other areas) in the absence of rheumatoid arthritis. Rheumatoid nodules can also appear in areas of the body other than the skin.
Devonian nodular limestone Concretionary nodular limestone at Jinshitan Coastal National Geopark, Dalian, China. In geology and particularly in sedimentology, a nodule is a small, irregularly rounded knot, mass, or lump of a mineral or mineral aggregate that typically has a contrasting composition from the enclosing sediment or sedimentary rock.
For example, my partial molar pregnancy caused me to develop atypical placental site nodules (APSN) — which my OB-GYN and Dr. Liu knew needed further, serious investigation.
Colloid nodules may be initially identified as an unspecified kind of thyroid nodule. Follow-up examinations typically include an ultrasound if it is unclear whether or not there really is a nodule present. Once the presence of a nodule has been confirmed, the determination of the kind of thyroid nodule is done by fine needle aspiration biopsy. [7]