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Polycystin 1. Polycystin 1 ( PC1) is a protein that in humans is encoded by the PKD1 gene. [5] [6] Mutations of PKD1 are associated with most cases of autosomal dominant polycystic kidney disease, a severe hereditary disorder of the kidneys characterised by the development of renal cysts and severe kidney dysfunction. [7]
Proprotein convertase 1, also known as prohormone convertase, prohormone convertase 3, or neuroendocrine convertase 1 and often abbreviated as PC1/3 is an enzyme that in humans is encoded by the PCSK1 gene. PCSK1 and PCSK2 differentially cleave proopiomelanocortin and they act together to process proinsulin and proglucagon in pancreatic islets.
Proprotein convertases (PPCs) are a family of proteins that activate other proteins. Many proteins are inactive when they are first synthesized, because they contain chains of amino acids that block their activity. Proprotein convertases remove those chains and activate the protein. The prototypical proprotein convertase is furin. [1]
Proprotein convertase 2 ( PC2) also known as prohormone convertase 2 or neuroendocrine convertase 2 ( NEC2) is a serine protease and proprotein convertase PC2, like proprotein convertase 1 (PC1), is an enzyme responsible for the first step in the maturation of many neuroendocrine peptides from their precursors, such as the conversion of ...
Polycystin 1, a protein in humans associated with autosomal dominant polycystic kidney disease. PC-1, a submarine telecommunications cable system (Pacific Crossing 1) PC1 cipher, used by the Amazon Kindle and some boot loaders. First principal component in principal component analysis, often used in genetic distance visualizations.
structure summary. Pro-opiomelanocortin ( POMC) is a precursor polypeptide with 241 amino acid residues. POMC is synthesized in corticotrophs of the anterior pituitary from the 267-amino-acid-long polypeptide precursor pre-pro-opiomelanocortin ( pre-POMC ), by the removal of a 26-amino-acid-long signal peptide sequence during translation. [5]
PC1 Tall Tales of the Wee Folk was written by John Nephew and published by TSR in 1989 as a sixty-four page book with an outer folder. The package also includes a thirty-two page adventure booklet, and features editing by Gary L. Thomas, a cover illustration by Keith Parkinson, and interior illustrations by Valerie Valusek. Reception
Olivetti computers. The Olivetti company, an Italian manufacturer of computers, tablets, smartphones, printers and other such business products as calculators and fax machines, was founded as a typewriter manufacturer by Camillo Olivetti in 1908 in the Turin commune of Ivrea, Italy. Olivetti was a pioneer in computer development, starting with ...