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A disulfiram-like drug is a drug that causes an adverse reaction to alcohol leading to nausea, vomiting, flushing, dizziness, throbbing headache, chest and abdominal discomfort, and general hangover-like symptoms among others.
Disulfiram is a medication used to support the treatment of chronic alcoholism by producing an acute sensitivity to ethanol (drinking alcohol). Disulfiram works by inhibiting the enzyme aldehyde dehydrogenase (specifically the ALDH2 enzyme [ 3 ] ), causing many of the effects of a hangover to be felt immediately following alcohol consumption.
The primary disabilities of FAS are the functional difficulties with which the child is born as a result of CNS damage due to prenatal alcohol exposure. [ 102 ] Often, primary disabilities are mistaken as behavior problems , but the underlying CNS damage is the originating source of a functional difficulty, [ 103 ] rather than a mental health ...
Disulfiram-like drugs that produce sensitivity to the toxic effects of alcohol (drug). Mostly acetaldehyde dehydrogenase inhibitors. Subcategories.
Disulfiram-alcohol reaction (DAR) is the effect of the interaction in the human body of alcohol drunk with disulfiram or some types of mushrooms. [ 1 ] [ 2 ] The DAR is key to disulfiram therapy that is widely used for alcohol-aversive treatment and management of other addictions (e.g. cocaine [ 3 ] [ 4 ] use).
[5] [6] It may also be characterized as intolerance causing hangover symptoms similar to the "disulfiram-like reaction" of aldehyde dehydrogenase deficiency or chronic fatigue syndrome. [ 7 ] [ 8 ] [ 9 ] Severe pain after drinking alcohol may indicate a more serious underlying condition.
Warning signs of alcoholism include the consumption of increasing amounts of alcohol and frequent intoxication, preoccupation with drinking to the exclusion of other activities, promises to quit drinking and failure to keep those promises, the inability to remember what was said or done while drinking (colloquially known as "blackouts ...
Disulfiram: Disulfiram is a prescribed medication which acts as an Aldehyde Dehydrogenase inhibitor, resulting in the accumulation of acetaldehyde. When Alcohol is consumed following Disulfiram, acetaldehyde builds up leading to unpleasant physiological effects (tachycardia, flushing, headache, nausea, and vomiting).