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Most abnormal results are mildly abnormal (ASC-US (typically 2–5% of Pap results) or low-grade squamous intraepithelial lesion (about 2% of results)), indicating HPV infection. [ citation needed ] Although most low-grade cervical dysplasias spontaneously regress without ever leading to cervical cancer , dysplasia can serve as an indication ...
High grade squamous intraepithelial lesion (HGSIL or HSIL) Squamous cell carcinoma; Atypical Glandular Cells not otherwise specified (AGC-NOS) Atypical Glandular Cells, suspicious for AIS or cancer (AGC-neoplastic) Adenocarcinoma in situ (AIS) The results are calculated differently following a Pap smear of the cervix. [citation needed]
Dysplasia is the earliest form of precancerous lesion which pathologists can recognize in a pap smear or in a biopsy. Dysplasia can be low grade or high grade. The risk of low-grade dysplasia transforming into high-grade dysplasia, and eventually cancer, is low. Treatment is usually straightforward.
What to do if you get an abnormal pap smear result. If you get an abnormal result from your pap test, don’t panic: “Many women have abnormal cervical cancer screening results and an abnormal ...
A squamous intraepithelial lesion (SIL) is an abnormal growth of epithelial cells on the surface of the cervix, commonly called squamous cells. This condition can lead to cervical cancer , but can be diagnosed using a Pap smear or a colposcopy .
ThinPrep pap smear with group of normal cervical cells on left and HPV-infected cells showing features typical of koilocytes: enlarged (x2 or x3) nuclei and hyperchromasia. A koilocyte is a squamous epithelial cell that has undergone a number of structural changes, which occur as a result of infection of the cell by human papillomavirus (HPV). [1]
VAIN can be detected by the presence of abnormal cells in a Papanicolaou test (Pap smear). [2] Like cervical intraepithelial neoplasia, VAIN comes in three stages, VAIN 1, 2, and 3. [3] In VAIN 1, a third of the thickness of the cells in the vaginal skin are abnormal, while in VAIN 3, the full thickness is affected. [3]
Pap smear results may be reported using the Bethesda system (see above). The sensitivity and specificity of this test were variable in a systematic review looking at accuracy of the test. An abnormal Pap smear result may lead to a recommendation for colposcopy of the cervix, an in office procedure during which the cervix is examined under ...