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Normal arterial blood oxygen saturation levels in humans are 96–100 percent. [1] If the level is below 90 percent, it is considered low and called hypoxemia . [ 2 ] Arterial blood oxygen levels below 80 percent may compromise organ function, such as the brain and heart, and should be promptly addressed.
Older children will often squat instinctively during a tet spell. [17] This increases systemic vascular resistance and allows for a temporary reversal of the shunt. It increases pressure on the left side of the heart, decreasing the right to left shunt, thus decreasing the amount of deoxygenated blood entering the systemic circulation. [21] [22]
High-flow therapy has been successfully implemented in infants and older children. The cannula improves the respiratory distress, the oxygen saturation, and the patient's comfort. Its mechanism of action is the application of mild positive airway pressure and lung volume recruitment. [16]
The body in hypovolemic shock prioritizes getting oxygen to the brain and heart, which reduces blood flow to nonvital organs and extremities, causing them to grow cold, look mottled, and exhibit delayed capillary refill. [3] The lack of adequate oxygen delivery ultimately leads to a worsening increase in the acidity of the blood (acidosis). [3]
Oxygen saturation is measured in the right hand and either foot. [35] A screening is considered positive if: Oxygen saturation < 90 % in either extremity, Oxygen saturation 90-94 % in both extremities on 3 measurements separated by an hour each, Oxygen saturation difference > 3 % between both extremities on 3 measurements separated by an hour each.
Ideally, the oxygen provided via ventilation would be just enough to saturate the blood fully. In the typical adult, 1 litre of blood can hold about 200 mL of oxygen; 1 litre of dry air has about 210 mL of oxygen. Therefore, under these conditions, the ideal ventilation perfusion ratio would be about 0.95.