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Acitretin, sold under the brand names Neotigason [2] and Soriatane, [5] is a second-generation retinoid.It is taken orally, and is typically used for psoriasis. [6]Acitretin is an oral retinoid used in the treatment of severe resistant psoriasis.
Tazarotene, sold under the brand name Tazorac, among others, is a third-generation prescription topical retinoid. [2] [3] It is primarily used for the treatment of plaque psoriasis and acne. [4] Tazarotene is also used as a therapeutic for photoaged and photodamaged skin. [4] It is a member of the acetylenic class of retinoids. [4]
Synthetic retinoids are utilized in cosmetic formulations, clinical dermatology, and the treatment of some forms of cancer. [1] Retinoids have many important functions throughout the body, including in vision, [2] regulation of skin proliferation and differentiation, growth of bone tissue, immune function, [3] and male fertility. [4]
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Etretinate (trade name Tegison) is a medication developed by Hoffmann–La Roche that was approved by the FDA in 1986 to treat severe psoriasis. It is a second-generation retinoid. [2] It was subsequently removed from the Canadian market in 1996 and the United States market in 1998 due to the high risk of birth defects.
Fenretinide (N-(4-hydroxyphenyl)retinamide; 4-HPR) is a synthetic retinoid derivative. Retinoids are substances related to vitamin A. It has been investigated for potential use in the treatment of cancer, as well as in the treatment of cystic fibrosis, [1] rheumatoid arthritis, acne, psoriasis, and has been found to also slow the production and accumulation of a toxin that leads to vision loss ...
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