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Cannabidiol (CBD) is a phytocannabinoid, one of 113 identified cannabinoids in cannabis plants, along with tetrahydrocannabinol (THC), and accounts for up to 40% of the plant's extract. [17] Medically, it is an anticonvulsant used to treat multiple forms of epilepsy. [4]
Despite the CBD and THC having the same molecular weight, multiple analytical methods are able to differentiate them. [11] "on the recovery of both THC (86.7−90.0%) and CBD (92.3−95.6%). The slightly lower recovery of THC can be explained by the fact that THC is less polar than CBD and more likely to remain in the nonpolar sunflower oil." [11]
Cannabinoids (/ k ə ˈ n æ b ə n ɔɪ d z ˌ ˈ k æ n ə b ə n ɔɪ d z /) are compounds found in the cannabis plant or synthetic compounds that can interact with the endocannabinoid system. [1] [2] The most notable cannabinoid is the phytocannabinoid tetrahydrocannabinol (THC) (Delta-9-THC), the primary intoxicating compound in cannabis.
CBD shares a precursor with THC and is the main cannabinoid in CBD-dominant Cannabis strains. CBD has been shown to play a role in preventing the short-term memory loss associated with THC. [29] There is tentative evidence that CBD has an anti-psychotic effect, but research in this area is limited. [30] [24]
CBD commonly refers to: Cannabidiol, a drug component of cannabis; Central business district, of a city; CBD may also refer to: Biology. Ecology.
Δ-6-cannabidiol (Delta-6-CBD, ∆ 6-CBD, sometimes alternatively numbered as ∆ 3-CBD) is a positional isomer of cannabidiol, found in only trace amounts in natural cannabis plants but readily synthesised from cannabidiol by base-catalysed migration of the double bond.
CBD is a 5-HT 1A receptor agonist, which is under laboratory research to determine if it has an anxiolytic effect. [141] It is often claimed that sativa strains provide a more stimulating psychoactive high while indica strains are more sedating with a body high. [142] However, this is disputed by researchers. [143]
The two cannabinoids usually produced in greatest abundance are cannabidiol (CBD) and/or Δ 9-tetrahydrocannabinol (THC), but only THC is psychoactive. [55] Since the early 1970s, Cannabis plants have been categorized by their chemical phenotype or "chemotype", based on the overall amount of THC produced, and on the ratio of THC to CBD. [56]