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Leukoplakia is, therefore, the most common premalignant lesion that occurs in the mouth. [41] Leukoplakia is more common in middle-aged and elderly males. [30] The prevalence increases with increasing age. [2] In areas of the world where smokeless tobacco use is common, there is a higher prevalence. [2]
Hairy leukoplakia is a white patch on the side of the tongue with a corrugated or hairy appearance. It is caused by Epstein-Barr virus (EBV) and occurs usually in persons who are immunocompromised , especially those with human immunodeficiency virus infection/ acquired immunodeficiency syndrome (HIV/AIDS).
Tongue diseases can be congenital or acquired, and are multiple in number. ... Oral hairy leukoplakia (seen in people with immunosuppression, ...
People with EBV could have oral hair leukoplakia, white, sometimes hairy, patches on the tongue; people with HPV could have papilloma bumps; and people with herpes develop cold sore blisters on ...
The frenulum should be centered under the tongue. Abnormal findings includes marked redness, cyanosis or extreme pallor. Diseases include scrotal or fissured tongue, migratory glossitis (geographic tongue), atrophic glossitis, black hairy tongue, caviar lesions, carcinoma, macroglossia, candidiasis, aphthous ulcer and leukoplakia.
Oral leukoplakia (white patch) on the left tongue. Proven to be severe dysplasia on biopsy. A premalignant (or precancerous) lesion is defined as "a benign, morphologically altered tissue that has a greater than normal risk of malignant transformation." There are several different types of premalignant lesion that occur in the mouth.
Hairy tongue may be confused with hairy leukoplakia, however the latter usually occurs on the sides of the tongue and is associated with an opportunistic infection with Epstein–Barr virus on a background immunocompromise (almost always human immunodeficiency virus infection but rarely other conditions which suppress the immune system).
Another term for hyperplastic candidiasis is "candidal leukoplakia". This term is a largely historical synonym for this subtype of candidiasis, rather than a true leukoplakia. [11] Indeed, it can be clinically indistinguishable from true leukoplakia, but tissue biopsy shows candidal hyphae invading the epithelium.