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  2. Human germline engineering - Wikipedia

    en.wikipedia.org/wiki/Human_germline_engineering

    There was a similar result in a study at the University of Bogota, Colombia, where students as well as professors generally agreed that therapeutic genome editing is acceptable, while non-therapeutic genome editing is not. [2] There is also debate on if there can be a defined distinction between therapeutic and non-therapeutic germline editing.

  3. Genome editing - Wikipedia

    en.wikipedia.org/wiki/Genome_editing

    Genome editing, or genome engineering, or gene editing, is a type of genetic engineering in which DNA is inserted, deleted, modified or replaced in the genome of a living organism. Unlike early genetic engineering techniques that randomly insert genetic material into a host genome, genome editing targets the insertions to site-specific locations.

  4. Gene targeting - Wikipedia

    en.wikipedia.org/wiki/Gene_targeting

    Because gene editing makes smaller changes to endogenous DNA, many mutations created through genome-editing could in theory occur through natural mutagenesis or, in the context of plants, through mutation breeding which is part of conventional breeding (in contrast the insertion of a transgene to create a Genetically Modified Organism (GMO ...

  5. Humans are 60 percent the same as chickens in one ... - AOL

    www.aol.com/article/2016/05/10/humans-are-60...

    In a 2004 paper published in the journal Nature, the International Chicken Genome Sequencing Consortium found that although a chicken doesn't have as much DNA as a human, it has about the same ...

  6. Genetic engineering techniques - Wikipedia

    en.wikipedia.org/wiki/Genetic_engineering_techniques

    Genome editing uses artificially engineered nucleases that create specific double-stranded breaks at desired locations in the genome. The breaks are subject to cellular DNA repair processes that can be exploited for targeted gene knock-out, correction or insertion at high frequencies.

  7. He Jiankui affair - Wikipedia

    en.wikipedia.org/wiki/He_Jiankui_affair

    The American Society of Human Genetics had declared in 2017 that the basic research on in vitro human genome editing on embryos and gametes should be promoted but that "At this time, given the nature and number of unanswered scientific, ethical, and policy questions, it is inappropriate to perform germline gene editing that culminates in human ...

  8. Prime editing - Wikipedia

    en.wikipedia.org/wiki/Prime_editing

    Prime editing was developed in the lab of David R. Liu at the Broad Institute and disclosed in Anzalone et al. (2019). [13] Since then prime editing and the research that produced it have received widespread scientific acclaim, [14] [6] [15] being called "revolutionary" [7] and an important part of the future of editing. [13]

  9. CRISPR gene editing - Wikipedia

    en.wikipedia.org/wiki/CRISPR_gene_editing

    CRISPR-Cas9 genome editing techniques have many potential applications. The use of the CRISPR-Cas9-gRNA complex for genome editing [10] was the AAAS's choice for Breakthrough of the Year in 2015. [11] Many bioethical concerns have been raised about the prospect of using CRISPR for germline editing, especially in human embryos. [12]

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