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Ascaricides are drugs to treat ascariasis that is caused by infections with parasitic nematodes (roundworms) of the genus Ascaris (giant intestinal roundworms).The large roundworm of pigs (Ascaris suum) typically infects pigs while Ascaris lumbricoides affects human populations, typically in sub-tropical and tropical areas with poor sanitation.
Ascariasis is a disease caused by the parasitic roundworm Ascaris lumbricoides. [1] Infections have no symptoms in more than 85% of cases, especially if the number of worms is small. [1] Symptoms increase with the number of worms present and may include shortness of breath and fever at the beginning of the disease. [1]
Ascaris lumbricoides is a large parasitic roundworm of the genus Ascaris. It is the most common parasitic worm in humans. [1] An estimated 807 million–1.2 billion people are infected with Ascaris lumbricoides worldwide. [2] People living in tropical and subtropical countries are at greater risk of infection.
Mebendazole (MBZ), sold under the brand name Vermox among others, is a medication used to treat a number of parasitic worm infestations. [5] This includes ascariasis, pinworm infection, hookworm infections, guinea worm infections and hydatid disease, among others. [5] It has been used for treatment of giardiasis but is not a preferred agent.
Ascaris and hookworm eggs become infective as they develop into larvae in soil. Infection occurs when vegetables and fruits, contaminated with soil-infested eggs, are consumed; or when hands or fingers have been contaminated with dirt carrying the eggs are put in the mouth. On the other hand, hookworm eggs are not directly infective.
A. lumbricoides is the largest intestinal roundworm and is the most common helminth infection of humans worldwide. Infestation can cause morbidity by compromising nutritional status, [ 3 ] affecting cognitive processes, [ 4 ] inducing tissue reactions such as granuloma to larval stages, and by causing intestinal obstruction , which can be fatal.
Ascaris infection: Antimesenteric splitting of the outer layers of the bowel wall due to a large amount of ascaris (South Africa) The signs and symptoms of helminthiasis depend on a number of factors including: the site of the infestation within the body; the type of worm involved; the number of worms and their volume; the type of damage the ...
Only a few roundworm eggs are necessary to cause larva migrans in human children or adults. However, visceral larva migrans seems to affect children aged 1–4 more often while ocular larva migrans more frequently affects children aged 7–8. Between 4.6% and 23% of U.S. children have been infected with the dog roundworm egg.