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Generalized bullous fixed drug eruption (GBFDE) most commonly refers to a drug reaction in the erythema multiforme group. [ 3 ] : 129 These are uncommon reactions to medications, with an incidence of 0.4 to 1.2 per million person-years for toxic epidermal necrolysis and 1.2 to 6.0 per million person-years for Stevens–Johnson syndrome .
Treatment typically takes place in hospital such as in a burn unit or intensive care unit. [3] [7] Efforts include stopping the cause, pain medication, and antihistamines. [3] [4] Antibiotics, intravenous immunoglobulins, and corticosteroids may also be used. [3] [4] Treatments do not typically change the course of the underlying disease. [3]
Warfarin-induced skin necrosis is a condition in which skin and subcutaneous tissue necrosis (tissue death) occurs due to acquired protein C deficiency following treatment with anti-vitamin K anticoagulants (4-hydroxycoumarins, such as warfarin). [1] Warfarin necrosis is a rare but severe complication of treatment with warfarin or related ...
Fixed drug reactions are common and so named because they recur at the same site with each exposure to a particular medication. [1] Medications inducing fixed drug eruptions are usually those taken intermittently.
Fever and a non specific skin eruption – with reddening and swelling of the skin – are the most common symptoms of NEH. Patients usually present with the skin eruption 1-2 weeks after use of the cytotoxic drug. Sometimes, the skin eruption can be painful. Skin eruptions can be located on the extremities, trunk, and face.
Early stage sepsis-associated purpura fulminans may be reversible with quick therapeutic intervention. [2] [7] Treatment is mainly removing the underlying cause and degree of clotting abnormalities and with supportive treatment (antibiotics, volume expansion, tissue oxygenation, etc.). Thus, treatment includes aggressive management of the ...
Photos of what pregnancy tissue from early abortions at 5 to 9 weeks actually looks like have gone viral.. The images, which were originally shared by MYA Network — a network of physicians who ...
Anticoagulant-induced skin necrosis; Anticonvulsant hypersensitivity syndrome; Bromoderma; Bullous drug reaction (bullous drug eruption, generalized bullous fixed drug eruption, multilocular bullous fixed drug eruption) Chemotherapy-induced acral erythema (palmoplantar erythrodysesthesia syndrome) Chemotherapy-induced hyperpigmentation; Drug ...