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Gestational diabetes can develop in dogs as well. It can be prevented by behavioral and dietary management. [13] Diabetes insipidus, which has nothing to do with blood sugar, but is a condition of insufficient antidiuretic hormone or resistance to it, also exists in dogs. [14] [15]
Diabetes insipidus (DI) is a condition characterized by large amounts of dilute urine and increased thirst. [1] The amount of urine produced can be nearly 20 liters per day. [ 1 ] Reduction of fluid has little effect on the concentration of the urine. [ 1 ]
Diabetes insipidus* in dogs can be central, caused by a lack of antidiuretic hormone (ADH), or nephrogenic, caused by a lack of response of the kidneys to ADH. Neither form is common. Central diabetes insipidus (CDI) is usually idiopathic, but can also be caused by head trauma [125] or tumors of the brain.
In regard to diabetes insipidus, treatment became available before the causes of the disease were clarified. The discovery of an antidiuretic substance extracted from the pituitary gland by researchers in Italy (A. Farini and B. Ceccaroni) and Germany (R. Von den Velden) in 1913 paved the way for treatment.
Desmopressin is used in the treatment of central diabetes insipidus (DI) as a replacement for endogenous antidiuretic hormone (ADH) that is in insufficient quantity due to decreased or non-existent secretion or production of ADH by the posterior pituitary or hypothalamus, respectively.
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