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  2. Multiple myeloma - Wikipedia

    en.wikipedia.org/wiki/Multiple_myeloma

    Multiple myeloma (MM), also known as plasma cell myeloma and simply myeloma, is a cancer of plasma cells, a type of white blood cell that normally produces antibodies. [6] Often, no symptoms are noticed initially. [10] As it progresses, bone pain, anemia, renal insufficiency, and infections may occur. [10]

  3. Plasma cell dyscrasias - Wikipedia

    en.wikipedia.org/wiki/Plasma_cell_dyscrasias

    They are less likely than multiple myeloma patients to have lytic bone lesions. In several studies of patients with either form of plasma cell leukemia, the disease was associated with clonal IgG in 28% to 56% of cases, IgA in 4% to 7% of cases, and a light chain in 23% to 44% of cases; 0-12% of patients had no myeloma protein.

  4. Plasma cell leukemia - Wikipedia

    en.wikipedia.org/wiki/Plasma_cell_leukemia

    Secondary PCL (sPCL) is diagnosed in 1-4% of patients known to have had multiple myeloma for a median time of ~21 months. It is the terminal phase of these patients' myeloma disease. sPCL patients typically are highly symptomatic due to extensive disease with malignant plasma cell infiltrations in, and failures of, not only the bone marrow but also other organs.

  5. 13q deletion syndrome - Wikipedia

    en.wikipedia.org/wiki/13q_deletion_syndrome

    Affected individuals may have a somewhat shortened lifespan without treatment. The maximum lifespan without treatment is 67 years. When a 13q deletion is detected, such as in a bone marrow biopsy for Multiple Myeloma, chemo treatments in recent years have the ability to extend life expectancy without limitations depending on response to treatments.

  6. POEMS syndrome - Wikipedia

    en.wikipedia.org/wiki/POEMS_syndrome

    Treatment of patients with this POEMS syndrome variant who have evidence of bone lesions and/or myeloma proteins are the same as those for POEMS syndrome patients. In the absence of these features, treatment with rituximab , a monoclonal antibody preparation directed against B cells bearing the CD20 antigen, or siltuximab , a monoclonal ...

  7. Multiple myeloma gets new attention after Bruce ... - AOL

    www.aol.com/news/multiple-myeloma-gets-attention...

    “The average myeloma patient, independent of race or ethnicity, sees their primary care provider three times with signs and symptoms that are consistent with myeloma before the diagnosis is ...

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