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In medicine, ROC analysis has been extensively used in the evaluation of diagnostic tests. [57] [58] ROC curves are also used extensively in epidemiology and medical research and are frequently mentioned in conjunction with evidence-based medicine. In radiology, ROC analysis is a common technique to evaluate new radiology techniques. [59]
An image of different ROC curves is shown in Figure 1. ROC curves provide a simple visual method for one to determine the boundary limit (or the separation threshold) of a biomarker or a combination of biomarkers for the optimal combination of sensitivity and specificity. The AUC (area under the curve) of the ROC curve reflects the overall ...
An example of ROC curve and the area under the curve (AUC). The area under the ROC curve (AUC) [1] [2] is often used to summarize in a single number the diagnostic ability of the classifier. The AUC is simply defined as the area of the ROC space that lies below the ROC curve. However, in the ROC space there are regions where the values of FPR ...
Youden's index is often used in conjunction with receiver operating characteristic (ROC) analysis. [3] The index is defined for all points of an ROC curve, and the maximum value of the index may be used as a criterion for selecting the optimum cut-off point when a diagnostic test gives a numeric rather than a dichotomous result.
2 Interpretation. 3 Relation to other ... The value a can be used to plot a summary ROC (SROC) curve. [5] [6] Example
Survival analysis includes Cox regression (Proportional hazards model) and Kaplan–Meier survival analysis. Procedures for method evaluation and method comparison include ROC curve analysis, [6] Bland–Altman plot, [7] as well as Deming and Passing–Bablok regression. [8]
At any given point in the ROC curve, it is possible to glean values for the ratios of false alarms/(false alarms+correct rejections) and hits/(hits+misses). For example, at threshold 74, it is evident that the x coordinate is 0.2 and the y coordinate is 0.3.
The area under the effect curve (AUEC) is an integral of the effect of a drug over time, estimated as a previously-established function of concentration. It was proposed to be used instead of AUC in animal-to-human dose translation, as computer simulation shows that it could cope better with half-life and dosing schedule variations than AUC.