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meta-Cresol, also 3-methylphenol, is an organic compound with the formula CH 3 C 6 H 4 (OH). It is a colourless, viscous liquid that is used as an intermediate in the production of other chemicals. It is a derivative of phenol and is an isomer of p-cresol and o-cresol. [3]
In its chemical structure, a molecule of cresol has a methyl group substituted onto the ring of phenol. There are three forms of cresol: ortho-cresol (o-cresol), meta-cresol (m-cresol), and para-cresol (p-cresol). These forms occur separately or as a mixture, which can also be called cresol or more specifically, tricresol.
In female elephants, the two compounds 3-ethyl phenol and 2-ethyl 4,5 dimethylphenol have been detected in urine samples. [70] Temporal glands secretion examination showed the presence of phenol, m-cresol and p-cresol (4-methyl phenol) during musth in male elephants. [71] [72] [73] p-Cresol and o-cresol are also components of the human sweat.
p-Cresol is a major component in pig odor. [11] Temporal glands secretion examination showed the presence of phenol and p-cresol during musth in male elephants. [12] [13] It is one of the very few compounds to attract the orchid bee Euglossa cyanura and has been used to capture and study the species.
o-Toluidine is absorbed through inhalation and dermal contact as well as from the gastrointestinal tract. [19] [13] [20] [21]The metabolism of o-toluidine involves many competing activating and deactivating pathways, including N-acetylation, N-oxidation, and N-hydroxylation, and ring oxidation.
AMC is a derivative of m-cresol, with a pentyl group attached to the sixth carbon atom. The pure substance melts at 24 °C (75 °F), and boils between 137 and 139 °C (279 and 282 °F) at a pressure of 6.7 kilopascals (50 mmHg). It is soluble in water, ethanol, acetone, diethylether, and oil. [6]
In ortho-substitution, two substituents occupy positions next to each other, which may be numbered 1 and 2.In the diagram, these positions are marked R and ortho.; In meta-substitution, the substituents occupy positions 1 and 3 (corresponding to R and meta in the diagram).
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