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The glomerulus (pl.: glomeruli) is a network of small blood vessels (capillaries) known as a tuft, located at the beginning of a nephron in the kidney. Each of the two kidneys contains about one million nephrons. The tuft is structurally supported by the mesangium (the space between the blood vessels), composed of intraglomerular mesangial cells.
Diagram of the circulation related to a single glomerulus, associated tubule, and collecting system The renal corpuscle in the cortex (outer layer) of the kidney. At the top, the renal corpuscle containing the glomerulus. The filtered blood exits into the renal tubule as filtrate, at right. At left, blood flows from the afferent arteriole (red ...
The nephron is the minute or microscopic structural and functional unit of the kidney. It is composed of a renal corpuscle and a renal tubule. The renal corpuscle consists of a tuft of capillaries called a glomerulus and a cup-shaped structure called Bowman's capsule. The renal tubule extends from the capsule.
Renal histology is the study of the microscopic structure of the kidney. The adult human kidney contains at least 26 distinct cell types, [25] including epithelial, endothelial, stromal and smooth muscle cells. Distinct cell types include: Kidney glomerulus parietal cell; Kidney glomerulus podocyte; Intraglomerular mesangial cell
The glomerular basement membrane of the kidney is the basal lamina layer of the glomerulus.The glomerular endothelial cells, the glomerular basement membrane, and the filtration slits between the podocytes perform the filtration function of the glomerulus, separating the blood in the capillaries from the filtrate that forms in Bowman's capsule. [1]
Bowman's capsule (or the Bowman capsule, capsula glomeruli, or glomerular capsule) is a cup-like sac at the beginning of the tubular component of a nephron in the mammalian kidney that performs the first step in the filtration of blood to form urine. A glomerulus is enclosed in the sac. Fluids from blood in the glomerulus are collected in the ...
[17] [6] [18] Differences in kidney structure are the result of adaptations during evolution to variations in body mass and habitats (in particular, aridity) between species. [19] [20] [12] The cortex and medulla of the kidney contain nephrons, [21] each of which consists of a glomerulus and a complex tubular system. [22]
The collecting duct system is the final component of the kidney to influence the body's electrolyte and fluid balance. In humans, the system accounts for 4–5% of the kidney's reabsorption of sodium and 5% of the kidney's reabsorption of water. At times of extreme dehydration, over 24% of the filtered water may be reabsorbed in the collecting ...