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Therefore, lactase persistence is often cited as an example of both recent human evolution [15] and, as lactase persistence is a genetic trait but animal husbandry a cultural trait, gene-culture coevolution in the mutual human-animal symbiosis initiated with the advent of agriculture. [56]
Lactose intolerance is the ancestral state of all humans before the recent evolution of lactase persistence in some cultures, which extends lactose tolerance into adulthood. [9] Lactase persistence evolved in several populations independently, probably as an adaptation to the domestication of dairy animals around 10,000 years ago.
The timeline of human evolution outlines the major events in the evolutionary lineage of the modern human species, Homo sapiens, ... [74] or lactase persistence. ...
Lactase persistence is a rare ability among mammals. [74] Because it involves a single gene, it is a simple example of convergent evolution in humans. Other examples of convergent evolution, such as the light skin of Europeans and East Asians or the various means of resistance to malaria, are much more complicated. [16]
Studies have linked the occurrence of lactase persistence to two different single-nucleotide polymorphisms about 14 and 22 kilobases upstream of the 5'-end of the LPH gene. [26] Both mutations, C→T at position -13910 and G→ A at position -22018, have been independently linked to lactase persistence. [27]
Dual inheritance theory (DIT), also known as gene–culture coevolution or biocultural evolution, [1] was developed in the 1960s through early 1980s to explain how human behavior is a product of two different and interacting evolutionary processes: genetic evolution and cultural evolution.
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In 2004 he led a study to show that most lactase persistent Africans did not have the same mutation causing it as Europeans. [8] In 2007, in collaboration with Joachim Burger 's group in Mainz, Germany, he showed that the genetic variant that causes lactase persistence in most Europeans (-13,910*T) was rare or absent in early farmers from ...