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Pirenoxine (abbreviated PRX, trade name Catalin) is a medication used in the possible treatment and prevention of cataracts. A report in the Inorganic Chemistry journal s howed that in liquid solutions, pirenoxine could cause decreased cloudiness of a crystallin solution produced to mimic the environment of the eye.
Intravitreal injection is the method of administration of drugs into the eye by injection with a fine needle. The medication will be directly applied into the vitreous humor. [1] It is used to treat various eye diseases, such as age-related macular degeneration (AMD), diabetic retinopathy, and infections inside the eye such as endophthalmitis. [1]
Researchers have recently developed a new drug that will ultimately shrink down and dissolve cataracts -- the leading cause of human blindness that affects tens of millions of people worldwide.
At some point—usually as you enter middle age—most people develop this eye condition, which is a clouding of the eye’s lens that can get progressively worse and impair your vision.
The most important factor that must be taken into account when designing any type of drug delivery device, and specifically ocular devices, is the release rate of a drug. As discussed previously, the deliver rate and kinetics associated with drugs to the eye can reach levels that are toxic to the eye or could even cause undesirable side effects.
Common side effects include red eyes, dry eyes, change in color of the eyes, blurry vision, and cataracts. [ 5 ] [ 6 ] [ 4 ] Use during pregnancy or breastfeeding is generally not recommended. [ 1 ] [ 6 ] [ 4 ] It is a prostaglandin analog and works by increasing the outflow of aqueous fluid from the eyes.
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