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A recent large-scale study found that severe depression in patients with bipolar disorder responds no better to a combination of antidepressant medications and mood stabilizers than it does to mood stabilizers alone and that antidepressant use does not hasten the emergence of manic symptoms in patients with bipolar disorder. [40]
The poor response from some bipolar patients to treatment has given evidence to the concept of treatment-resistant bipolar disorder. [163] [164] Guidelines to the definition of treatment-resistant bipolar disorder and evidence-based options for its management were reviewed in 2020. [165]
BD-NOS is a mood disorder and one of four subtypes on the bipolar spectrum, which also includes bipolar I disorder, bipolar II disorder, and cyclothymia. [1] BD-NOS was a classification in the DSM-IV and has since been changed to Bipolar "Other Specified" and "Unspecified" in the 2013 released DSM-5 (American Psychiatric Association, 2013).
The Bipolar Spectrum Diagnostic Scale (BSDS) is a psychiatric self-rating scale created by Ronald Pies in screening for bipolar disorder (BD). [1] Its initial version consists of a descriptive narrative aimed to capture the nuances and milder variants of BD. [ 2 ]
Low scores of 5 and below indicate a very low risk of a bipolar diagnosis. High scores of 18 and over indicate a high risk of a diagnosis of bipolar disorder, increasing the likelihood by a factor of seven or greater. [26] [5] Several peer-reviewed research studies support the P-GBI as a reliable and valid measure of bipolar in children and ...
Bipolar disorder is a mental disorder with cyclical periods of depression and periods of elevated mood. [1] The elevated mood is significant and is known as mania , a severe elevation that can be accompanied by psychosis in some cases, or hypomania , a milder form of mania.