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Medical condition Osteochondritis dissecans A large flap lesion in the femur head typical of late stage Osteochondritis dissecans. In this case, the lesion was caused by avascular necrosis of the bone just under the cartilage. Pronunciation / ˌ ɒ s t i. oʊ k ɒ n ˈ d r aɪ t ɪ s ˈ d ɪ s ɪ k æ n z / Specialty Orthopedic surgery Osteochondritis dissecans (OCD or OD) is a joint disorder ...
Osteochondrosis is a developmental disease. It usually occurs in an early stage of life. It has personified features as focal chondronecrosis and confinement of growth cartilage due to a failing of endochondral ossification. Fissures can develop from lesions over the top articular cartilage and form a cartilage flap and an osteochondral fragment.
Examples of this form of articulation are found in the hip, where the round head of the femur (ball) rests in the cup-like acetabulum (socket) of the pelvis; and in the shoulder joint, where the rounded upper extremity of the humerus (ball) rests in the cup-like glenoid fossa (socket) of the shoulder blade. [2]
Autologous articular cartilage transfer from a non-weight-bearing area to the damaged area, called osteochondral autograft transfer system, is one possible procedure that is being studied. [146] When the missing cartilage is a focal defect, autologous chondrocyte implantation is also an option.
The procedure is less effective in treating older patients, overweight patients, or a cartilage lesion larger than 2.5 cm. [11] Further on, chances are high that after only 1 or 2 years of the surgery symptoms start to return as the fibrocartilage wears away, forcing the patient to reengage in articular cartilage repair.
The osteochondral fracture occurs on the weight-bearing portion of the lateral condyle. Typically, the condyle will fracture (and the patella may dislocate) as a result of severe impaction from activities such as downhill skiing and parachuting. [1] Open reduction and internal fixation surgery is typically used to repair an osteochondral fracture.
The initiation of endochondral ossification starts by proliferation and condensation of mesenchymal cells in the area where the bone will eventually be formed. Subsequently, these mesenchymal progenitor cells differentiate into chondroblasts, which actively synthesize cartilage matrix components.
The cartilage cells or chondrocytes are contained in cavities in the matrix, called cartilage lacunae; around these, the matrix is arranged in concentric lines as if it had been formed in successive portions around the cartilage cells. This constitutes the so-called capsule of the space.