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Acute lung injury may cause pulmonary edema directly through injury to the vasculature and parenchyma of the lung, causes include: Inhalation of hot or toxic gases [12] (including vaping-associated lung injury) Pulmonary contusion, i.e., high-energy trauma (e.g. vehicle accidents) Aspiration, e.g., gastric fluid
Pathogenesis in pulmonary hypertension due to left heart disease (WHO Group II) is completely different in that constriction or damage to the pulmonary blood vessels is not the issue. Instead, the left heart fails to pump blood efficiently, leading to pooling of blood in the lungs and back pressure within the pulmonary system.
Pulmonary edema occurs when the pressure in blood vessels in the lung is raised because of obstruction to the removal of blood via the pulmonary veins. This is usually due to failure of the left ventricle of the heart. It can also occur in altitude sickness or on inhalation of toxic chemicals. Pulmonary edema produces shortness of breath.
The pathophysiology of acute respiratory distress syndrome involves fluid accumulation in the lungs not explained by heart failure (noncardiogenic pulmonary edema). It is typically provoked by an acute injury to the lungs that results in flooding of the lungs' microscopic air sacs responsible for the exchange of gases such as oxygen and carbon dioxide with capillaries in the lungs. [1]
Immersion causes increased external hydrostatic pressure, leading to redistribution of blood from the periphery to the chest, which increases cardiac filling pressures and stroke volume, and also reduces total lung capacity. There is a movement of fluid from the alveolar capillaries into the alveoli and extravascular lung tissues, which ...
A diagram explaining factors affecting arterial pressure. Pathophysiology is a study which explains the function of the body as it relates to diseases and conditions. The pathophysiology of hypertension is an area which attempts to explain mechanistically the causes of hypertension, which is a chronic disease characterized by elevation of blood pressure.