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  2. Radioimmunoprecipitation assay buffer - Wikipedia

    en.wikipedia.org/wiki/Radioimmunoprecipitation...

    Radioimmunoprecipitation assay buffer (RIPA buffer) is a lysis buffer used to lyse cells and tissue for the radio immunoprecipitation assay (RIPA). [1] [2] This buffer is more denaturing than NP-40 or Triton X-100 because it contains the ionic detergents SDS and sodium deoxycholate as active constituents and is particularly useful for disruption of nuclear membranes in the preparation of ...

  3. Lysis buffer - Wikipedia

    en.wikipedia.org/wiki/Lysis_buffer

    RIPA buffer is a commonly used lysis buffer for immunoprecipitation and general protein extraction from cells and tissues. The buffer can be stored without vanadate at 4 °C for up to 1 year. [10] RIPA buffer releases proteins from cells as well as disrupts most weak interactions between proteins. [9] Recipe: [10] 1% (w/w) Nonidet P-40 (NP-40)

  4. PMSF - Wikipedia

    en.wikipedia.org/wiki/PMSF

    In biochemistry, phenylmethylsulfonyl fluoride (PMSF) is a serine protease inhibitor (serine hydrolase inactivator) commonly used in the preparation of cell lysates. PMSF does not inactivate all serine proteases. [1] The effective concentration of PMSF is between 0.1 - 1 mM.

  5. Ristocetin-induced platelet aggregation - Wikipedia

    en.wikipedia.org/wiki/Ristocetin-induced...

    The ristocetin-induced platelet aggregation (RIPA) is an ex vivo assay for live platelet function. It measures platelet aggregation with the help of von Willebrand factor (vWF) and exogenous antibiotic ristocetin added in a graded fashion. [ 1 ]

  6. Protease inhibitor (biology) - Wikipedia

    en.wikipedia.org/wiki/Protease_inhibitor_(biology)

    Many naturally occurring protease inhibitors are proteins. [2] In medicine, protease inhibitor is often used interchangeably with alpha 1-antitrypsin (A1AT, which is abbreviated PI for this reason). [3] A1AT is indeed the protease inhibitor most often involved in disease, namely in alpha-1 antitrypsin deficiency.

  7. AEBSF - Wikipedia

    en.wikipedia.org/wiki/AEBSF

    AEBSF or 4-(2-aminoethyl)benzenesulfonyl fluoride hydrochloride is a water-soluble, irreversible serine protease inhibitor with a molecular weight of 239.5 Da. It inhibits proteases like chymotrypsin, kallikrein, plasmin, thrombin, and trypsin. The specificity is similar to the inhibitor PMSF, nevertheless AEBSF is more stable at low pH values ...