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It is also used for topical airway anaesthesia for procedures such as awake fibreoptic bronchoscopy or intubation. Although some absorption and systemic effects may occur, the use of cocaine as a topical anesthetic and vasoconstrictor is generally safe, rarely causing cardiovascular toxicity, glaucoma, and pupil dilation.
Cocaine's classification as a narcotic under U.S. legal code, as has been stretched to be medicinally rationalized such when defining terms very broadly (due to its topical numbing affect, hindering pain signals from CNS recognition via local anesthesia) usually considered an exaggeration of traditional medicine naming convention, in this ...
Many local anesthetics fall into two general chemical classes, amino esters (top) and amino amides (bottom). A local anesthetic (LA) is a medication that causes absence of all sensation (including pain) in a specific body part without loss of consciousness, [1] providing local anesthesia, as opposed to a general anesthetic, which eliminates all sensation in the entire body and causes ...
Leaves of the coca plant (Erythroxylum novogranatense var. Novogranatense), from which cocaine, a naturally occurring local anesthetic, is derived [1] [2]. An anesthetic (American English) or anaesthetic (British English; see spelling differences) is a drug used to induce anesthesia — in other words, to result in a temporary loss of sensation or awareness.
Topical tac is a topical anesthetic solution [1] introduced by Pryor et al. in 1980. It is a mixture of 5 to 12% tetracaine, 0.05% adrenaline, and 4 or 10% cocaine hydrochloride (hence the "TAC" nomenclature). It has been used in ear, nose, and throat surgery and in the emergency department where numbing of the surface is needed rapidly.
Drug-induced amnesia is amnesia caused by drugs. Amnesia may be therapeutic for medical treatment or for medical procedures, or it may be a side-effect of a drug, such as alcohol, or certain medications for psychiatric disorders, such as benzodiazepines. [1] It is seen also with slow acting parenteral general anaesthetics.
He proposed – mistakenly – that the cocaine was absorbed into the venous circulation and subsequently transported to the spinal cord. [ 14 ] Although Bier properly deserves credit for the introduction of spinal anesthesia into the clinical practice of medicine, it was Corning who created the experimental conditions that ultimately led to ...
[11] [12] TIVA has also been used for anesthetic delivery at sites of trauma such as serious accidents, disasters and wars. [1] The overall goals of TIVA include: [13] Smooth induction of anesthesia; Reliable and measurable maintenance of anesthesia; Rapid emergence out of the effects of infused drugs as soon as the infusion is terminated.