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Cell to Singularity began development in 2017, inspired by Computer Lunch co-founder Andrew Garrahan’s love of nature documentaries. [2] Wanting to create a game about science and history, Garrahan saw the emergent popularity of the incremental game genre as a good fit for the more relaxed pace of a documentary.
Two functions have been described for Y RNAs in the literature: As a repressor of Ro60, and as an initiation factor for DNA replication.Mutant human Y RNAs lacking the conserved binding site for Ro60 protein still support DNA replication, [3] indicating that binding to Ro protein and promoting DNA replication are two separable functions of Y RNAs.
Gametogenesis is a biological process by which diploid or haploid precursor cells undergo cell division and differentiation to form mature haploid gametes.Depending on the biological life cycle of the organism, gametogenesis occurs by meiotic division of diploid gametocytes into various gametes, or by mitosis.
The human Y chromosome is composed of about 62 million base pairs of DNA, making it similar in size to chromosome 19 and represents almost 2% of the total DNA in a male cell. [54] [55] The human Y chromosome carries 693 genes, 107 of which are protein-coding. [56]
In human genetics, a human Y-chromosome DNA haplogroup is a haplogroup defined by specific mutations in the non-recombining portions of DNA on the male-specific Y chromosome (Y-DNA). Individuals within a haplogroup share similar numbers of short tandem repeats (STRs) and single-nucleotide polymorphisms (SNPs). [ 2 ]
Haplogroup T-M184, also known as Haplogroup T, is a human Y-chromosome DNA haplogroup. The unique-event polymorphism that defines this clade is the single-nucleotide polymorphism known as M184. [4] Detailed representation of the presence of Haplogroup T in Europe and surrounding areas.
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The human genome is a complete set of nucleic acid sequences for humans, encoded as the DNA within each of the 24 distinct chromosomes in the cell nucleus. A small DNA molecule is found within individual mitochondria. These are usually treated separately as the nuclear genome and the mitochondrial genome. [1]