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Cocaine (from French cocaïne, from Spanish coca, ultimately from Quechua kúka) [13] is a tropane alkaloid that acts as a central nervous system (CNS) stimulant. As an extract, it is mainly used recreationally and often illegally for its euphoric and rewarding effects.
Dimethocaine is often abused as a legal substitute for cocaine. The drug is administered intravenously or nasally, because ingestion would lead to rapid hydrolyzation. [5] Its positive effects are euphoria, stimulation, increased talkativeness and mood lift. [6] However, because the drug acts similar as cocaine, it has comparable negative side ...
Crack cocaine is commonly used as a recreational drug. Effects of crack cocaine include euphoria, [11] supreme confidence, [12] loss of appetite, [11] insomnia, [11] alertness, [11] increased energy, [11] a craving for more cocaine, [12] and potential paranoia (ending after use).
Coca leaf is the raw material for the manufacture of the drug cocaine, a powerful stimulant and anaesthetic extracted chemically from large quantities of coca leaves. Today, since it has mostly been replaced as a medical anaesthetic by synthetic analogues such as procaine, cocaine is best known as an illegal recreational drug.
Cocaine is a relatively "balanced" inhibitor, although facilitation of dopaminergic neurotransmission is what has been linked to the reinforcing and addictive effects. In addition, cocaine has some serious limitations in terms of its cardiotoxicity [188] due to its local anesthetic activity. Thousands of cocaine users are admitted to emergency ...
Strasser likened cocaine to "caffeine on steroids" and told the disciplinary panel that, in small doses, cocaine can make the user more alert and attentive and "have a positive effect on someone's ...
Nevertheless, a slow onset, long-duration agonist seems like a reasonable approach. Phenyltropanes are widely used in animal studies of drug addiction as they share the stimulant properties and reinforcing effects of cocaine, but with higher potency, less non-specific binding which avoids the cardiotoxicity associated with cocaine. [13]
It really does pay to be positive and the benefits include enhanced health and longevity, happiness, career advancement, athletic performance, team building and financial success. Being positive ...