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Mitochondria are commonly between 0.75 and 3 μm 2 in cross section, [11] but vary considerably in size and structure. Unless specifically stained , they are not visible. In addition to supplying cellular energy, mitochondria are involved in other tasks, such as signaling , cellular differentiation , and cell death , as well as maintaining ...
Simplified cross-section of a mitochondrion and a submitochondrial particle, showing the particle's inverted membrane orientation. Whereas whole submitochondrial particles can perform oxidative phosphorylation yielding ATP, destabilized particles lacking F 1 particles consume oxygen and oxidize NADH without synthesizing ATP, and free F 1 particles catalyze the hydrolysis of ATP into ADP.
The inner mitochondrial membrane is both an electrical insulator and chemical barrier. Sophisticated ion transporters exist to allow specific molecules to cross this barrier. There are several antiport systems embedded in the inner membrane, allowing exchange of anions between the cytosol and the mitochondrial matrix. [7]
Simplified structure of a mitochondrion. The intermembrane space (IMS) is the space occurring between or involving two or more membranes. [1] In cell biology, it is most commonly described as the region between the inner membrane and the outer membrane of a mitochondrion or a chloroplast.
Mitochondrial matrix has a pH of about 7.8, which is higher than the pH of the intermembrane space of the mitochondria, which is around 7.0–7.4. [5] Mitochondrial DNA was discovered by Nash and Margit in 1963. One to many double stranded mainly circular DNA is present in mitochondrial matrix. Mitochondrial DNA is 1% of total DNA of a cell.
The inner membrane section currently says it is the site of "mitochondrial fusion and fission protein". While the inner membrane fusion protein OPA1 is located here, most of the time when we discuss "mito fusion" we are referring to the outer membrane (mediated by Mfn1 & 2, and adapters) or the mitochondrion as a whole (OMM and IMM).
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A crista (/ ˈ k r ɪ s t ə /; pl.: cristae) is a fold in the inner membrane of a mitochondrion.The name is from the Latin for crest or plume, and it gives the inner membrane its characteristic wrinkled shape, providing a large amount of surface area for chemical reactions to occur on.