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Acetylcholine (ACh) is an organic compound that functions in the brain and body of many types of animals (including humans) as a neurotransmitter. [1] Its name is derived from its chemical structure: it is an ester of acetic acid and choline. [2] Parts in the body that use or are affected by acetylcholine are referred to as cholinergic.
The main function of insect blood, hemolymph, is that of transport and it bathes the insect's body organs. Making up usually less than 25% of an insect's body weight, it transports hormones, nutrients and wastes and has a role in osmoregulation, temperature control, immunity, storage (water, carbohydrates and fats) and skeletal function.
In mammals, nicotinic acetylcholine receptors are located in cells of both the central nervous system and peripheral nervous systems. In insects, these receptors are limited to the central nervous system. Nicotinic acetylcholine receptors are activated by the neurotransmitter acetylcholine.
High-molecular-weight proteins that have been isolated from the Mediterranean black widow (L. tredecimguttatus) include the insect-specific neurotoxins α-latroinsectotoxin and δ-latroinsectotoxin, a neurotoxin affecting crustaceans known as latrocrustatoxin, and small peptides that inhibit angiotensin-1-converting enzyme.
The chemical works by interfering with the transmission of stimuli in the insect nervous system. Specifically, it causes a blockage of the nicotinergic neuronal pathway. By blocking nicotinic acetylcholine receptors, imidacloprid prevents acetylcholine from transmitting impulses between nerves, resulting in the insect's paralysis and eventual ...
Choline is a direct precursor of acetylcholine (ACh), a neurotransmitter of the central and peripheral nervous system that regulates a variety of autonomic, cognitive, and motor functions. SLC5A7 is a Na(+)- and Cl(-)- dependent high-affinity transporter that mediates the uptake of choline for acetylcholine synthesis in cholinergic neurons. [5] [6]
This glossary of entomology describes terms used in the formal study of insect species by entomologists.. When present, elytra of the Staphylinidae are markedly abbreviate. This fly in the genus Scaptomyza has clearly visible rows of para-sagittal acrostichal bristles on its thorax the alitrunk of aculeate Hymenoptera comprises the three thoracic segments, plus the propodeum, which strictly ...
Venom disrupters of acetylcholine neurotransmission generally penetrate the neuromuscular junction, where they interfere with either the production or reception of acetylcholine, or the hydrolysis of acetylcholine after it has achieved its function of neurotransmission; mamba fasciculins prevent the final stage of this process by binding to acetylcholinesterase and blocking its action on ...