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Leukemia cutis is the infiltration of neoplastic leukocytes or their precursors into the skin resulting in clinically identifiable cutaneous lesions. [1] This condition may be contrasted with leukemids , which are skin lesions that occur with leukemia, but which are not related to leukemic cell infiltration.
The skin can be involved in the form of leukemia cutis; Sweet's syndrome; or non-specific findings: flat lesions , raised lesion papules, pyoderma gangrenosum and vasculitis. [ 8 ] Some people with AML may experience swelling of the gums because of infiltration of leukemic cells into the gum tissue. [ 7 ]
Conventionally, a leukocytosis exceeding 50,000 WBC/mm 3 with a significant increase in early neutrophil precursors is referred to as a leukemoid reaction. [2] The peripheral blood smear may show myelocytes, metamyelocytes, promyelocytes, and rarely myeloblasts; however, there is a mixture of early mature neutrophil precursors, in contrast to the immature forms typically seen in acute leukemia.
Leukemia (also spelled leukaemia; ... This represents 2.9% of all cancers (excluding simple basal cell and squamous cell skin cancers) in the United States, ...
Subleukemic leukemia, also known as leukemia subleukemic and aleukemic leukemia cutis, is a rare, cancerous blood disease characterized by the presence of abnormal or atypical white blood cells in the peripheral blood while the total white blood cell count is within the normal range. It can also be characterized by leukemic cells in the skin ...
Blastic plasmacytoid dendritic cell neoplasm is an aggressive malignancy with features of cutaneous lymphoma (e.g. malignant plasmacytoid dendritic cell infiltrations into the skin to form single or multiple lesions) and/or leukemia (i.e. malignant plasmacytoid dendritic cells in blood and bone marrow). [2]
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