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Rheumatic fever can be prevented by effectively and promptly treating strep throat with antibiotics. [45] Globally, rheumatic fever is seen in populations that are socioeconomically disadvantaged and with limited access to health care. [46] Overcrowding [46] [47] and exposure to domestic air pollution [47] have been cited as associated risk ...
Recent figures quote the incidence of Acute Rheumatic Fever as 0.6–0.7/1,000 population in the United States and Japan compared with 15–21/1,000 population in Asia and Africa. [32] The prevalence of Acute Rheumatic Fever and Sydenham's Chorea has declined progressively in developed countries over the last decades.
In India, where the risk of rheumatic fever is higher, intramuscular benzathine penicillin G is the first choice for treatment. [16] Appropriate antibiotics decrease the average 3–5 day duration of symptoms by about one day, and also reduce contagiousness. [23]
Philip Showalter Hench (February 28, 1896 – March 30, 1965 [1]) was an American physician.Hench, along with his Mayo Clinic co-worker Edward Calvin Kendall and Swiss chemist Tadeus Reichstein was awarded the Nobel Prize for Physiology or Medicine in 1950 for the discovery of the hormone cortisone, and its application for the treatment of rheumatoid arthritis.
Acute rheumatic fever (ARF) is a complication of respiratory infections caused by GAS. The M-protein generates antibodies that cross-react with autoantigens on interstitial connective tissue, in particular of the endocardium and synovium, that can lead to significant clinical illness.
Common symptoms include fever, sore throat, and large lymph nodes. It is a contagious infection, spread by close contact with an infected individual. A definitive diagnosis is made based on the results of a throat culture. Antibiotics are useful to both prevent complications (such as rheumatic fever) and speed recovery. [21]
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Rheumatology covers more than 100 different complex diseases, collectively known as rheumatic diseases, which includes many forms of arthritis as well as lupus and Sjögren's syndrome. [1] Doctors who have undergone formal training in rheumatology are called rheumatologists .