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These symptoms generally begin with the or third cycle of treatment and can last long after treatment completion. Indeed, the “coasting” phenomenon mentioned in the Symptoms section is a direct effect of platinum agents. Of the platinum compounds, research has shown cisplatin to be the most frequently involved in peripheral neuropathy. [3]
After its expansion in 2014, it became the third largest cancer hospital in the United States. In December 2014, The James opened a new hospital. With more than 1.1 million square feet, and 21 floors, "the New James" is the third largest cancer hospital in the country. [ 5 ]
The James Cancer Hospital and Solove Research Institute. The Arthur G James Cancer Hospital and Richard J. Solove Research Institute is a dedicated cancer hospital and research center that is part of the university's Comprehensive Cancer Center, with a governance structure separate from, but coordinated with, Ohio State Wexner Medical Center.
Peripheral neuropathy may be classified according to the number and distribution of nerves affected (mononeuropathy, mononeuritis multiplex, or polyneuropathy), the type of nerve fiber predominantly affected (motor, sensory, autonomic), or the process affecting the nerves; e.g., inflammation (), compression (compression neuropathy), chemotherapy (chemotherapy-induced peripheral neuropathy).
Myelosuppression, peripheral neuropathy, anaphylaxis, nausea and vomiting (30-90%), hypokalaemia, metabolic acidosis, interstitial lung disease (uncommon), ototoxicity (rare), reversible posterior leucoencephalopathy syndrome (rare), immune-mediated cytopenias (rare) and hepatic sinusoidal obstruction syndrome (rare). 1.11 Miscellaneous others
The systems of the body most affected by chemotherapy drugs include visual and semantic memory, attention and motor coordination and executive functioning. [9] [10] These effects can impair a chemotherapy patient's ability to understand and make decisions regarding treatment, perform in school or employment and can reduce quality of life. [10]
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