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Thrombophilia (sometimes called hypercoagulability or a prothrombotic state) is an abnormality of blood coagulation that increases the risk of thrombosis (blood clots in blood vessels). [ 1 ] [ 2 ] Such abnormalities can be identified in 50% of people who have an episode of thrombosis (such as deep vein thrombosis in the leg) that was not ...
Thromboelastography (TEG) is a method of testing the efficiency of blood coagulation.It is a test mainly used in surgery and anesthesiology, although increasingly used in resuscitations in emergency departments, intensive care units, and labor and delivery suites.
APTEM test is an EXTEM based assay in which fibrinolysis is inhibited by aprotinin in the reagent. A significant improvement of the clot in APTEM compared to EXTEM allows to detect fulminant hyperfibrinolysis. Therefore, the test helps in identifying the necessity of administrating antifibrinolytic drugs. Furthermore, APTEM enables the ...
Thrombodynamics test. Non-homogenous: realization of the three-dimensional model of the clot growth; Use of platelet free plasma; Record of information about the clot formation as a diagram, giving the possibility to calculate the key parameters of the blood coagulation system; New test, not widely accepted; Overall hemostatic potential (OHP)
The activated protein C resistance (APCR) test is a coagulation test used in the evaluation and diagnosis of activated protein C (APC) resistance, a form of hypercoagulability. [ 1 ] [ 2 ] Hereditary APC resistance is usually caused by the factor V Leiden mutation, whereas acquired APC resistance has been linked to antiphospholipid antibodies ...
Antiphospholipid syndrome is known for causing arterial or venous blood clots, in any organ system, and pregnancy-related complications.While blood clots and pregnancy complications are the most common and diagnostic symptoms associated with APS, other organs and body parts may be affected like platelet levels, heart, kidneys, brain, and skin.
A thrombin generation assay (TGA) or thrombin generation test (TGT) is a global coagulation assay (GCA) and type of coagulation test which can be used to assess coagulation and thrombotic risk. [ 1 ] [ 2 ] [ 3 ] It is based on the potential of a plasma to generate thrombin over time, following activation of coagulation via addition of ...
The test is potentially useful in the evaluation of hypercoagulability, hypocoagulability, and fibrinolytic abnormalities. [1] [2] [3] It is able to detect hypercoagulability associated with pregnancy and estrogen/progestogen hormone therapy. [3] [4] The test has also been used to study coagulation in feminizing hormone therapy in transgender ...