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Eosinophilic bronchitis (EB) is a type of airway inflammation due to excessive mast cell recruitment and activation in the superficial airways as opposed to the smooth muscles of the airways as seen in asthma. [1] [2] It often results in a chronic cough. [1] Lung function tests are usually normal. [1] Inhaled corticosteroids are often an ...
Bronchial thermoplasty is the only treatment modality designed to combat a hallmark of airway remodelling; airway smooth muscle hypertrophy. The effects of bronchial thermoplasty on smooth muscle mass are seen up to at least 12 months post-treatment; however, the procedure does not seem to impact other features of airway remodelling. [4] Thus ...
Bronchoconstriction is defined as the narrowing of the airways in the lungs (bronchi and bronchioles). Air flow in air passages can get restricted in three ways: [3] a spasmodic state of the smooth muscles in bronchi and bronchioles; an inflammation in the middle layers of the bronchi and bronchioles; excessive production of mucus.
Acute bronchitis, also known as a chest cold, is short-term bronchitis – inflammation of the bronchi (large and medium-sized airways) of the lungs. [2] [1] The most common symptom is a cough. [1] Other symptoms include coughing up mucus, wheezing, shortness of breath, fever, and chest discomfort. [2] The infection may last from a few to ten ...
Bronchitis is inflammation of the bronchi (large and medium-sized airways) in the lungs that causes coughing. Bronchitis usually begins as an infection in the nose, ears, throat, or sinuses. The infection then makes its way down to the bronchi. Symptoms include coughing up sputum, wheezing, shortness of breath, and chest pain.
An airway obstruction can be caused by either an intraluminal mass such as a tumor or a foreign body. [31] The presence of an airway obstruction leads to a cycle of inflammation. [3] It is important to identify the presence of an obstruction because surgical resection is often curative if obstruction is the cause. [32]
Bronchial thermoplasty [1] is a treatment for severe asthma approved by the FDA in 2010 involving the delivery of controlled, therapeutic radiofrequency energy to the airway wall, thus heating the tissue and reducing the amount of smooth muscle present in the airway wall.
[4] [13] The presence of inflammation and infection in the airways also results in the production of excess mucus, which must be coughed up as sputum. [4] [6] The combination of inflammation, nodule development, infection, mucus, and frequent cough contributes to the breathing difficulties in DPB. [4] [5]