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Topiramate selectively inhibits cytosolic (type II) and membrane-associated (type IV) forms of carbonic anhydrase. Its action on carbonic anhydrase isoenzymes may contribute to the drug's side effects, including its propensity to cause metabolic acidosis and calcium phosphate kidney stones.
Topiramate Side Effects. Common side effects of topiramate include: Weight loss — you probably knew this one. Paresthesia (skin tingling or numbness) Fatigue. Dizziness. Somnolence (drowsiness)
Phentermine-topiramate (Qsymia®). This combination medication contains phentermine ... Less common (and more serious) side effects may include: Mood changes. Increased blood pressure.
The most common side effects are gastrointestinal, particularly nausea and diarrhea. ... Phentermine-topiramate. This is a combination of an appetite suppressant called phentermine and an ...
Common side effects include tingling, dizziness, trouble sleeping, and constipation. [3] Serious side effects may include suicide, abuse. [3] Use is not recommended during pregnancy. [1] Phentermine is a stimulant and appetite suppressant. [3] Topiramate is an anticonvulsant that has weight loss side effects. [3]
The newer drugs tend to have fewer side effects. [42] For newly diagnosed partial or mixed seizures, there is evidence for using gabapentin, lamotrigine, oxcarbazepine or topiramate as monotherapy. [42] Lamotrigine can be included in the options for children with newly diagnosed absence seizures. [42]