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  2. Prader–Willi syndrome - Wikipedia

    en.wikipedia.org/wiki/PraderWilli_syndrome

    PraderWilli syndrome (PWS) is a rare genetic disorder caused by a loss of function of specific genes on chromosome 15. [2] In newborns, symptoms include weak muscles, poor feeding, and slow development. [2] Beginning in childhood, those affected become constantly hungry, which often leads to obesity and type 2 diabetes. [2]

  3. Chromosomal deletion syndrome - Wikipedia

    en.wikipedia.org/wiki/Chromosomal_deletion_syndrome

    There are known three molecular causes of PraderWilli syndrome development. One of them consists in micro-deletions of the chromosome region 15q11–q13. 70% of patients present a 5–7-Mb de novo deletion in the proximal region of the paternal chromosome 15. The second frequent genetic abnormality (~ 25–30% of cases) is maternal ...

  4. Urban–Rogers–Meyer syndrome - Wikipedia

    en.wikipedia.org/wiki/Urban–Rogers–Meyer...

    Urban–Rogers–Meyer syndrome, also known as PraderWilli habitus, osteopenia, and camptodactyly or Urban syndrome, [1] is an extremely rare inherited congenital disorder first described by Urban et al. (1979).

  5. Heinrich Willi - Wikipedia

    en.wikipedia.org/wiki/Heinrich_Willi

    Heinrich Willi (4 March 1900 – 16 February 1971) was a Swiss pediatrician who specialised in neonatology and co-discovered PraderWilli syndrome with Andrea Prader. Biography [ edit ]

  6. Cryptorchidism - Wikipedia

    en.wikipedia.org/wiki/Cryptorchidism

    Cryptorchidism occurs at a much higher rate in a large number of congenital malformation syndromes. Among the more common are Down syndrome, [8] PraderWilli syndrome, and Noonan syndrome. In vitro fertilization, use of cosmetics by the mother, and pre-eclampsia have also been recognized as risk factors for development of cryptorchidism. [11]

  7. Childhood obesity - Wikipedia

    en.wikipedia.org/wiki/Childhood_obesity

    PraderWilli syndrome, with an incidence between 1 in 12,000 and 1 in 15,000 live births, is characterized by hyperphagia and food preoccupations which leads to rapid weight gain in those affected. Bardet–Biedl syndrome

  8. Breech birth - Wikipedia

    en.wikipedia.org/wiki/Breech_birth

    PraderWilli syndrome 50%, Werdnig–Hoffman syndrome 10%; Smith–Lemli–Opitz syndrome 40%; Fetal alcohol syndrome 40%; Potter anomaly 36%; Zellweger syndrome 27%; Myotonic dystrophy 21%, 13 trisomy syndrome 12%; 18 trisomy syndrome 43%; 21 trisomy syndrome 5%; de Lange syndrome 10%; Anencephalus 6–18%, Spina bifida 20–30%; Congenital ...

  9. Comparative genomic hybridization - Wikipedia

    en.wikipedia.org/wiki/Comparative_genomic...

    PraderWilli syndrome (PWS) is a paternal structural abnormality involving 15q11-13, while a maternal aberration in the same region causes Angelman syndrome (AS). In both syndromes, the majority of cases (75%) are the result of a 3–5 Mb deletion of the PWS/AS critical region. [ 26 ]