Search results
Results From The WOW.Com Content Network
Zinc fingers were first identified in a study of transcription in the African clawed frog, Xenopus laevis in the laboratory of Aaron Klug.A study of the transcription of a particular RNA sequence revealed that the binding strength of a small transcription factor (transcription factor IIIA; TFIIIA) was due to the presence of zinc-coordinating finger-like structures. [6]
In molecular genetics, the Krüppel-like family of transcription factors (KLFs) are a set of eukaryotic C2H2 zinc finger DNA-binding proteins that regulate gene expression. This family has been expanded to also include the Sp transcription factor and related proteins, forming the Sp/KLF family. [1]
The KRAB domain had initially been identified in 1988 as a periodic array of leucine residues separated by six amino acids 5’ to the zinc finger region of KOX1/ZNF10 [7] coined heptad repeat of leucines (also known as a leucine zipper). [8] Later, this domain was named in association with the C2H2-Zinc finger proteins Krüppel associated box ...
Transmembrane protein 98 is a single-pass membrane protein that in humans is ... plants, or fungi. Genus and Species Common Name ... C2H2 zinc finger transcription ...
Group III WRKY proteins have a C2HC zinc finger instead of the C2H2 motif of group I and II factors. The structure of several plant WRKY domains has been elucidated using crystallography [6] and nuclear magnetic resonance spectroscopy. [7] The different groups of WRKY Domains in flowering plants
Zinc finger transcription factors or ZF-TFs, are transcription factors composed of a zinc finger-binding domain and any of a variety of transcription-factor effector-domains that exert their modulatory effect in the vicinity of any sequence to which the protein domain binds. [1] Zinc finger protein transcription factors can be encoded by genes ...
The BTB/POZ domain (BTB for BR-C, ttk and bab [2] or POZ for Pox virus and Zinc finger [3]) is a structural domain found in proteins across the domain Eukarya. [4] Given its prevalence in eukaryotes and its absence in Archaea and bacteria, it likely arose after the origin of eukaryotes. [5]
In molecular biology, the FLYWCH zinc finger is a zinc finger domain. It is found in a number of eukaryotic proteins . FLYWCH is a C2H2 -type zinc finger characterised by five conserved hydrophobic residues, containing the conserved sequence motif: