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Chromium toxicity refers to any poisonous toxic effect in an organism or cell that results from exposure to specific forms of chromium—especially hexavalent chromium. [1] Hexavalent chromium and its compounds are toxic when inhaled or ingested. Trivalent chromium is a trace mineral that is essential to human nutrition.
Although the safety of daily chromium doses of up to 1,000 μg has been shown, there are some reports of serious adverse effects by using chromium picolinate, including kidney failure from a six-week course of 600 μg per day and liver disease after using 1,200 to 2,400 μg per day over four to five months. [2]
Nephrotoxicity is toxicity in the kidneys. It is a poisonous effect of some substances, both toxic chemicals and medications, on kidney function. [1] There are various forms, [2] and some drugs may affect kidney function in more than one way. Nephrotoxins are substances displaying nephrotoxicity.
California has set a limit for the toxic heavy metal hexavalent chromium in drinking water. Advocates have called for a stricter limit, warning of health risks.
Many metals, particularly heavy metals are toxic, but some are essential, and some, such as bismuth, have a low toxicity. Metals in an oxidation state abnormal to the body may also become toxic: chromium(III) is an essential trace element, but chromium(VI) is a carcinogen. Only soluble metal-containing compounds are toxic.
In its trivalent form, chromium is relatively harmless and abundant. But heat that is more than 390 degrees Fahrenheit can catalyze chemical reactions that transform it into its more dangerous ...
Foods with higher levels of acid have been linked to the progression of kidney failure, says Davar. Alkaline foods like green, leafy vegetables may be a better option, but as always, consult your ...
Ingestion of, or exposure to, excessive quantities can be toxic. However, insufficient plasma or tissue levels of certain trace metals can cause pathology, as is the case with iron. Trace metals within the human body include iron, lithium, zinc, copper, chromium, nickel, cobalt, vanadium, molybdenum, manganese and others. [1] [2] [3]