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Colorized scanning electron micrograph of a human neutrophil ingesting MRSA. Methicillin-resistant Staphylococcus aureus (MRSA) is a group of gram-positive bacteria that are genetically distinct from other strains of Staphylococcus aureus. MRSA is responsible for several difficult-to-treat infections in humans.
Methicillin-resistant Staphylococcus aureus (MRSA, often pronounced / ˈ m ɜːr s ə / or / ɛ m ɑːr ɛ s eɪ /), is one of a number of greatly feared strains of S. aureus which have become resistant to most β-lactam antibiotics. For this reason, vancomycin, a glycopeptide antibiotic, is commonly used to combat MRSA. Vancomycin inhibits the ...
ST8:USA300 is a strain of community-associated methicillin-resistant Staphylococcus aureus that has emerged as a particularly antibiotic resistant epidemic that is responsible for rapidly progressive, fatal diseases including necrotizing pneumonia, severe sepsis and necrotizing fasciitis. [1]
This test was recommended the standard by the Clinical and Laboratory Standards Institute in 2004 for its use against MRSA. [3] Testing for inducible clindamycin resistance is typically performed in strains of Staphylococcus , β-hemolytic streptococci, and Streptococcus pneumoniae that demonstrate erythromycin resistance and clindamycin ...
MRSA ST398 is a clonal complex 398 (CC398). This means that the strain had emerged in a human clinic, without any obvious or understandable causes. MRSA ST398, a specific strain of MRSA, is commonly found in livestock, and can cause infections in humans who come into contact with infected animals. [1]
It is present in the majority [1] of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) isolates studied [2] [3] and is the cause of necrotic lesions involving the skin or mucosa, including necrotic hemorrhagic pneumonia. PVL creates pores in the membranes of infected cells.
Although antibiotic sensitivity testing is done in a laboratory , the information provided about this is often clinically relevant to the antibiotics in a person . [36] Sometimes, a decision must be made for some bacteria as to whether they are the cause of an infection, or simply commensal bacteria or contaminants, [ 28 ] such as ...
The infection can be life-threatening. Problematically, methicillin-resistant Staphylococcus aureus (MRSA) has become a major cause of hospital-acquired infections. MRSA has also been recognized with increasing frequency in community-acquired infections. [7]