Ad
related to: basement membrane vs basal surface
Search results
Results From The WOW.Com Content Network
The basement membrane, also known as base membrane, is a thin, pliable sheet-like type of extracellular matrix that provides cell and tissue support and acts as a platform for complex signalling. [ 1 ] [ 2 ] The basement membrane sits between epithelial tissues including mesothelium and endothelium , and the underlying connective tissue.
The glomerular basement membrane is a special case, consisting of a fusion of the podocyte and endothelial basal laminas, and lacking a lamina reticularis. Thus, it consists of an especially thick lamina densa, sandwiched on its inside and outside by layers of lamina lucida / rara (one from each cell type).
A secondary role of the basolateral membrane is to allow the recycling of desirable substrates, such as glucose, that have been rescued from the lumen of the tubule to be secreted into the interstitial fluids. [2] Basal and lateral membranes share common determinants, the proteins LLGL1, DLG1, and SCRIB. These three proteins all localize to the ...
The basement membrane acts as a selectively permeable membrane that determines which substances will be able to enter the epithelium. [2]: 3 The basal lamina is made up of laminin (glycoproteins) secreted by epithelial cells. The reticular lamina beneath the basal lamina is made up of collagen proteins secreted by connective tissue.
Basement membrane assembly is a cooperative process in which laminins polymerise through their N-terminal domain (LN or domain VI) and anchor to the cell surface through their G domains. Netrins may also associate with this network through heterotypic LN domain interactions. [28]
The basolateral membrane refers to both the lateral membrane where cell-cell junctions connect neighboring cells and to the basal membrane where cells are attached to the basement membrane, a thin sheet of extracellular matrix proteins that separates the epithelial sheet from underlying cells and connective tissue.
A basal cell is a general cell type that is present in many forms of epithelial tissue throughout the body. Basal cells are located between the basement membrane and the remainder of the epithelium, effectively functioning as an anchor for the epithelial layer and an important mechanism in the maintenance of intraorgan homeostasis.
The lamina propria is a thin layer of loose (areolar) connective tissue, which lies beneath the epithelium, and together with the epithelium and basement membrane constitutes the mucosa. As its Latin name indicates, it is a characteristic component of the mucosa, or the mucosa's "own special layer."