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Narcolepsy is a chronic neurological disorder that impairs the ability to regulate sleep–wake cycles, and specifically impacts REM (rapid eye movement) sleep. [1] The pentad symptoms of narcolepsy include excessive daytime sleepiness (EDS), sleep-related hallucinations, sleep paralysis, disturbed nocturnal sleep (DNS), and cataplexy. [1]
Pitolisant is indicated in adults for the treatment of narcolepsy. [3] [4] Narcolepsy is a chronic sleep disorder that causes overwhelming daytime drowsiness. [4] Pitolisant is also indicated to improve alertness and reduce excessive daytime sleepiness in adults with obstructive sleep apnea. [5] [12]
Sodium oxybate, sold under the brand name Xyrem among others, is a medication used to treat symptoms of narcolepsy: sudden muscle weakness and excessive daytime sleepiness. [3] [7] [8] It is used sometimes in France and Italy as an anesthetic given intravenously.
Treatment for narcolepsy and cataplexy can be divided to those that act on the excessive daytime sleepiness (EDS) and those that improve cataplexy. Most patients require lifelong use of medications. [15] Most treatments in humans will act only symptomatically and do not target the loss of the orexin-producing neurons. [16]
Most commonly prescribed for ADHD, Adderall can also be used to treat narcolepsy (a sleep disorder that causes excessive daytime tiredness or the sudden need to sleep).
Narcolepsy. Medicare will cover a narcolepsy sleep study with proof from the sleep clinic that the condition significantly affects your health and well-being. You may need up to three tests for ...
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