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Infective endocarditis is associated with 18% in-hospital mortality. [24] However, adult patients with congenital heart disease can have relatively lower mortality down to 5% due to younger age, right-sided endocarditis and management by multidisciplinary teams. As many as 50% of people with infective endocarditis may experience embolic ...
The nodes are commonly indicative of subacute bacterial endocarditis. [4] 10–25% of endocarditis patients will have Osler's nodes. [5] Other signs of endocarditis include Roth's spots and Janeway lesions. The latter, which also occur on the palms and soles, can be differentiated from Osler's nodes because they are non-tender. [3]
Another form of sterile endocarditis is termed Libman–Sacks endocarditis; this form occurs more often in patients with lupus erythematosus and is thought to be due to the deposition of immune complexes. [2] Like NBTE, Libman-Sacks endocarditis involves small vegetations, while infective endocarditis is composed of large vegetations. [2]
Subacute bacterial endocarditis, abbreviated SBE, is a type of endocarditis (more specifically, infective endocarditis). [5] Subacute bacterial endocarditis can be considered a form of type III hypersensitivity .
Diagnosing the cause of infective endocarditis, typically involves getting positive blood culture, which is literally growing bacteria from a blood sample. Echocardiography can also be used to visualize the heart and look for vegetations or more subtle clues like the way the valve’s moving.
Janeway lesions are rare, non-tender, small erythematous or haemorrhagic macular, papular or nodular lesions on the palms or soles only a few millimeters in diameter that are associated with infective endocarditis and often indistinguishable from Osler's nodes. [1]
Endocarditis is the inflammation of the endocardium; Pancarditis, also called perimyoendocarditis, is the inflammation of the entire heart: the pericardium, the myocardium and the endocardium; Reflux carditis refers to a possible outcome of esophageal reflux [citation needed] (also known as GERD), and involves inflammation of the esophagus ...
Roth's spots, also known as Litten spots or the Litten sign, [1] are non-specific red lesions with white or pale centres, seen on the retina of the eye and although traditionally associated with infective endocarditis, can occur in a number of other conditions including hypertension, diabetes, collagen vascular disease, extreme hypoxia, leukemia and HIV.