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About 90% of cases of herpes encephalitis are caused by herpes simplex virus-1 (HSV-1), the same virus that causes cold sores. According to a 2006 estimate, 57% of American adults were infected with HSV-1, [3] which is spread through droplets, casual contact and sometimes sexual contact, though most infected people never have cold sores.
Brain scan, done by MRI, can determine inflammation and differentiate from other possible causes. EEG, in monitoring brain activity, encephalitis will produce abnormal signal. Lumbar puncture (spinal tap), this helps determine via a test using the cerebral-spinal fluid, obtained from the lumbar region. Blood test; Urine analysis
Herpes meningitis is typically self-limiting over 2 weeks without treatment. However, empirical use of antiviral medications such as acyclovir are considered in cases of suspected HSV meningitis to prevent progression to the more rapid and fatal HSV meningoencephalitis. [7] HSV-2 is the most common herpes virus that causes meningitis. [3]
For herpes simplex virus encephalitis, a CT scan may show low-density lesions in the temporal lobe. These lesions usually appear 3 to 5 days after the start of the infection. Japanese encephalitis often has distinct EEG patterns, including diffuse delta activity with spikes, diffuse continuous delta activity, and alpha coma activity.
Many viral infections of the central nervous system occur in seasonal peaks or as epidemics, whereas others, such as herpes simplex encephalitis, are sporadic. In endemic areas it is mostly a disease of children, but as the disease spreads to new regions, or nonimmune travelers visit endemic regions, nonimmune adults are also affected.
Not long after, the seizures started up again and the family was told that Caper would need a second surgery to remove more pieces of his brain. “The first surgery had a 60% chance of giving him ...
Neurotropic viruses that cause infection include Japanese Encephalitis, Venezuelan Equine Encephalitis, and California encephalitis viruses; polio, coxsackie, echo, mumps, measles, influenza and rabies, as well as diseases caused by members of the family Herpesviridae such as herpes simplex, varicella-zoster, Epstein–Barr, cytomegalovirus and HHV-6 viruses. [2]
Brain MRI is the mainstay of initial investigation pointing to limbic lobe pathology revealing increased T2 signal involving one or both temporal lobes in most cases. [ 22 ] [ 14 ] Serial MRI in LE starts as an acute disease with uni- or bilateral swollen temporomesial structures that are hyperintense on fluid attenuation inversion recovery and ...