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2,4-Dinitrophenol (2,4-DNP or simply DNP) is an organic compound with the formula HOC 6 H 3 (NO 2) 2. It has been used in explosives manufacturing and as a pesticide and herbicide. In humans, DNP causes dose-dependent mitochondrial uncoupling , causing the rapid loss of ATP as heat and leading to uncontrolled hyperthermia —up to 44 °C (111 ...
A prodrug of DNP, HU6, has been tested in clinical trials for weight loss and fatty liver disease. [22] Fibroblast growth factor-21 receptor agonists and drugs increasing FGF-21 activity are being investigated for obesity-related diseases; they can increase energy expenditure and several have been tested in humans. [23] [24]
Lifestyle medicine (LM) is a branch of medicine focused on preventive healthcare and self-care dealing with prevention, research, education, and treatment of disorders caused by lifestyle factors and preventable causes of death such as nutrition, physical inactivity, chronic stress, and self-destructive behaviors including the consumption of tobacco products and drug or alcohol abuse. [1]
HU6 is a prodrug of the mitochondrial uncoupler 2,4-dinitrophenol (DNP) that is intended to "minimize the rapid absorption and high peak blood concentrations of DNP to provide a wider therapeutic index and improve safety."
The Doctor of Nursing Practice (DNP) is a professional degree in nursing in the United States of America. In the United States, the DNP is one of three doctoral degrees in nursing, the other two being the research degree PhD and the Doctor of Nursing Science. [1] The DNP program may include clinical/residency hours as well as a final scholarly ...
This funky health trend quickly gained traction when aesthetic nurse practitioner Miranda Wilson, ... Ayurveda is a holistic system of medicine that began over 3,000 years ago in India, ...
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